WebApr 11, 2024 · Causes of Severe Hand Pain and Treatment. 1. Complex Regional Pain Syndrome. Complex Regional Pain Syndrome is a chronic condition causing intense pain, discoloration, stiffness, and even swelling in certain extremities of your body. Most often occurring in the hands, it can occur in other parts of the body, such as arms, legs, and feet. WebJul 11, 2024 · Tendonitis of the hand causes severe pain with movement of the hand. Tendonitis is an inflammation of the tendon. Tendons of the hand are thin, flat and white in color. Inflammation of the tendon sheath results …
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