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P53 antibody cst

Webp53 Antibody 可识别内源水平的 p53 总蛋白。 该抗体结合位点位于人 p53 蛋白的氨基末端和 DNA 结合域。 物种反应性: 人, 猴 来源/纯化 使用全长人 p53 融合蛋白对动物进行免疫接种来产生多克隆抗体。 通过蛋白质 A 和肽亲和色谱纯化抗体。 背景 p53 肿瘤抑制蛋白在 DNA 损伤和其他基因组畸变的细胞应答中起重要作用。 p53 的激活会导致细胞周期停滞 … Webp53 Antibody recognizes endogenous levels of total p53 protein. This antibody binding has been mapped to the amino terminus and DNA binding domain of human p53 protein. Species Reactivity: Human, Monkey Source …

P53 antibody knockout validation Cell Signaling 2524

WebRabbit [KO Validated] p53 Rabbit mAb (A22449), validaed in WB,IHC and tested in Human,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody. WebApr 16, 2024 · The tumor suppressor p53 is mutated in approximately half of all human cancers. p53 can induce apoptosis through mitochondrial membrane permeabilization by … seneca ins co inc california https://keatorphoto.com

Understanding p53 functions through p53 antibodies - PubMed

WebThe p53 Antibody Sampler Kit provides an economical means of detecting p53 activity using modification-specific and control antibodies. The kit includes enough antibody to … WebFor immunofluorescence staining of p53, slides of CIA joint synovial tissues were incubated with anti-p53 antibody (sc-126, Santa Cruz Biotechnology) and anti-vimentin antibody (ab92547, Abcam) at 4 °C overnight, then followed by secondary antibodies incubation with anti-rabbit IgG (#8889, Cell Signaling Technology) and anti-mouse IgG (#4408 ... WebPhospho-p53 (Ser15) Antibody (MA5-15229) in ICC/IF. Immunofluorescence analysis of Phospho-p53 (Ser15) was performed using 70% confluent log phase HCT116 cells treated with etoposide. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 … seneca high school gym

CX-4945 inhibits fibroblast-like synoviocytes functions

Category:A common Gain of function of p53 cancer mutants in inducing …

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P53 antibody cst

Acetyl-p53 (Lys382) Antibody - Cell Signaling Technology

WebJul 30, 2024 · p53-R273H promotes cell migration via downregulation of KLF6 and E-cadherin expression. p53 is the most frequently mutated gene in human cancers. Webp53 Antibody (DO-1) is an IgG 2a κ mouse monoclonal p53 antibody (also designated tumor suppressor protein p53 antibody or TP53 antibody) suitable for the detection of the p53 …

P53 antibody cst

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WebProduct Name p53 (Ab-15) Antibody Host Species Rabbit Clonality Polyclonal Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Applications WB IHC IF Species Reactivity Hu Ms Rt WebApr 1, 2024 · The early anti-p53 antibodies contributed to the recognition of p53 accumulation as a common feature of cancer cells and to our understanding of p53 DNA-binding and transcription activities. They led to the concept that conformational changes can facilitate p53's activity as a growth inhibitory protein.

WebThis antibody clone recognises both wild-type and mutant forms of p53 in human samples. It is not designed to recognise any specific p53 mutation. We have confirmed this experimentally and have been able to detect p53 … WebMar 3, 2024 · Targeting a neoantigen derived from a common TP53 mutation - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. sharing sensitive information, make sure you’re on a federal

WebAnti-p53 (phospho S15) antibody [EPR64 (N)] - ChIP Grade (ab223868) Research with confidence – consistent and reproducible results with every batch. Long-term and … WebAnti-Mutant p53 antibodies are available from several suppliers. The full protein is reported to be 393 amino acid residues in length. Based on antigen name, there may be canine, porcine, monkey, mouse and rat variants of this protein. The Mutant p53 antigen is a documented cancer marker.

WebNational Center for Biotechnology Information

WebThen, the sections were incubated with rabbit anti-PD-L1 monoclonal antibody (#13684, 1:100 dilution; Cell Signaling Technology, Danvers, MA, USA) and anti-p53 monoclonal antibody (#86630, 1:200 dilution; Cell Signaling Technology) respectively overnight at 4°C. seneca hill manor oswego ny 13126WebApr 16, 2024 · The tumor suppressor p53 is mutated in approximately half of all human cancers. p53 can induce apoptosis through mitochondrial membrane permeabilization by interacting with and antagonizing the... seneca host nameWebThis antibody has been shown to work in applications such as: Precipitation, ChIP, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot. p53 (7F5) Rabbit mAb detects endogenous levels of total p53 protein. seneca hills pet resortWebApr 7, 2024 · As a transcription factor, TP53 encodes the p53 protein that regulates ~ 300 target genes that coordinate diverse cellular effector functions including cell cycle arrest, apoptotic cell death, damaged DNA repair, free radical … seneca housing incWebPolyclonal Antibody for studying p53 (Lys382) acetylate. Cited in 295 publications. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously … seneca holdings llc addressWebThe p53 (1C12) Mouse mAb Antibody was generated using tumor protein p53 as the antigen. It reacts with Human, Mouse, Rat, Hamster, and Non-Human Primate. This … seneca hickory stick gcWebSep 3, 2024 · Product-Name : p53 Antibody Size : 100 ul Price- (USD) : 235 USD Species-x-Reactivity : H, R, Mk Applications : Chromatin Immunoprecipitation Product-Category : Cell Cycle / Checkpoint Control Shipping-Temp : AMBIENT Storage-Temp : -20°C Product-Type : Polyclonal Antibody MW : 53 Host : Rabbit Target : p53 Primary-Protein : p53 Alt-Names : seneca house bromsgrove