Hybrid mouse diversity panel hmdp strains

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August undefined, 2024

WebGenomeMUSter is a comprehensive SNP data resource that includes typed, sequenced, and imputed genotypes of 581 inbred mouse strains. Genotypes from ten datasets … WebThe Hybrid Mouse Diversity Panel (HMDP) is a collection of approximately 100 well-characterized inbred strains of mice that can be used to analyze the genetic and environmental factors underlying complex traits. While not nearly as powerful for mapping genetic loci contributing First, environmental factors can be controlled.

Isoproterenol-Induced Heart Failure Mouse Model Using

Web26 aug. 2024 · Mitochondria play a key role in the normal function of the heart as well as in the pathogenesis of diseases. We report analysis of common genetic variations contributing to mitochondrial and heart functions using an integrative proteomics approach in a panel of inbred mouse strains called the Hybrid Mouse Diversity Panel (HMDP). We … Web为此，作者利用了约100个不同遗传背景的近交小鼠品系，即Hybrid Mouse Diversity Panel（HMDP）。通过对HMDP中约100个小鼠品系的肝脏和心脏组织进行高通量RNA … jena laolagi

Hybrid mouse diversity panel: a panel of inbred mouse strains …

Web7 nov. 2016 · The Hybrid Mouse Diversity Panel (HMDP) is a collection of approximately 100 well-characterized inbred strains of mice that can be used to analyze the genetic and … http://zarlab.cs.ucla.edu/tag/hmdp/ WebSuch strains can expand the HMDP panel to more than 260 strains. Recombinant inbred congenic, consomic and Genome Tagged Mice ( Peters et al. 2007) can also be added. As mentioned earlier, HMDP data can be integrated with that from other panels, notably the Collaborative Cross. jena la radar map

A GWAS approach identifies Dapp1 as a determinant of air …

非酒精性脂肪肝病的性别差异：用大数据回答大问题 BMC Journal

Web30 apr. 2024 · Abstract This is the first genome-wide association study (GWAS) with the Hybrid Mouse Diversity Panel (HMDP) to define the genetic landscape of the auditory hair cell synapse and the... Web18 jan. 2013 · RNA from cortical bone (femoral diaphysis free of marrow) were profiled from 99 Hybrid Mouse Diversity Panel strains were profiled. Sixteen-week old male mice were used in this study. A total of 1-3 mice per strain were arrayed. Contributor(s) Farber CR: Citation(s) 21490954, 23300464: Submission date: Feb 24, 2011: Last update date: Jan … jenal arifinWebSexually Dimorphic Relationships Among Saa3 (Serum Amyloid A3) Inflammation, and Cholesterol Metabolism Modulate Atherosclerosis in Mice Arteriosclerosis Thrombosis … jena lariche obituary

"Web26 aug. 2024 · Mitochondria play a key role in the normal function of the heart as well as in the pathogenesis of diseases. We report analysis of common genetic variations … " - Hybrid mouse diversity panel hmdp strains

Hybrid mouse diversity panel hmdp strains

Genetic Architecture of Heart Mitochondrial Proteome influencing ...

Web24 jul. 2024 · Here, focusing on macrophage responses to lipopolysaccharide (LPS), we use the hybrid mouse diversity panel (HMDP) of 83 inbred strains as a surrogate for … Web24 mrt. 2024 · Our aim was to characterize the genetic architecture of carbon tetrachloride (CCl4)-induced liver fibrosis using the Hybrid Mouse Diversity Panel (HMDP), a panel …

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WebThe Hybrid Mouse Diversity Panel (HMDP) is a collection of approximately 100 well-characterized inbred strains of mice that can be used to analyze the genetic and … http://zarlab.cs.ucla.edu/tag/hmdp/

WebThe Institutional Care and Use Committee (IACUC) at University of Southern California endorsed the animal protocol for the Hybrid Mouse Diversity Panel (HMDP) inbred strains (IACUC 12033). Strains and genotypes are accessible from Jackson Labs ( www.jax.org). WebThe Hybrid Mouse Diversity Panel (HMDP) is a collection of approximately 100 well-characterized inbred strains of mice that can be used to analyze the... DOAJ is a …

Web31 jul. 2024 · We examined an isoproterenol heart failure model across a panel of diverse inbred strains of mice, the Hybrid Mouse Diversity Panel (HMDP), using left atrial (LA) … Web23 dec. 2024 · To address these challenges, we used the Hybrid Mouse Diversity Panel to elucidate the genetic architecture of asthma-related phenotypes in mice and identify loci that are associated with airway hyperreactivity (AHR) under control exposure conditions and in response to diesel exhaust particles (DEP), as a model traffic-related air pollutant.

Web18 feb. 2024 · We examined natural genetic variation in lipopolysaccharide (LPS)-induced PD across a panel of inbred mouse strains, the hybrid …

Web15 aug. 2012 · Map of linkage disequilibrium (LD) blocks along the genome in the hybrid mouse diversity panel (HMDP) population. The LD blocks were determined using ~860,000 SNPs that have >5 % minor allele frequency (mean and median minor allele frequency of 28 and 31 %) and are polymorphic between the strains. jena larosWeb31 mrt. 2024 · In this body of work, male C57BL/6J mice with humanised lipid profiles, via transgenic expression of the human cholesteryl ester transferase protein (CETP) transgene (Jiang et al., 1992) and the human apolipoprotein (APO)E*3-Leiden variant (van den Maagdenberg et al., 1993), were interbred with female HMDP mice to generate a panel … lake carl etling oklahomaWeb4 apr. 2024 · Figure. Identification of Ascc2 as a causal gene for heart failure with preserved ejection fraction. A, Identification of Ascc2 as a cis-regulator of diastolic function.Ai, Experimental design for the development of isoproterenol (ISO)–induced cardiomyopathy across hybrid mouse diversity panel (HMDP) strains.Nine-week-old female mice from … lake carolina walking trailsWeb31 jul. 2024 · The Hybrid Mouse Diversity Panel (HMDP) consists of ~100 well-characterized inbred mouse strains that can be used to study genetic and environmental factors underlying complex traits . The HMDP, with a fully annotated genome and an easily controlled environment, can be readily manipulated to create a disease model for in … jena la stampaWebThe Hybrid Mouse Diversity Panel (HMDP) Over 100 fully genotyped genetically unique inbred mice Large diversity in clinically-relevant parameters Ability to perform . systems … jena la shoppingWeb10 jul. 2024 · In our previously published study performed across 105 Hybrid Mouse Diversity Panel (HMDP) strains, we used a dosage of 30 mg/kg/d over 21 days via the osmotic pump implanted intraperitoneally [8, 9]. We observed striking interstrain variation in terms of response to interventricular wall and left ventricular mass hypertrophy, ... lake carolina painWeb1 okt. 2016 · We describe the first genome-wide association study (GWAS) for NIHL in a large and well-characterized population of inbred mouse strains, known as the Hybrid Mouse Diversity Panel (HMDP). We recorded auditory brainstem response (ABR) thresholds both pre and post 2-hr exposure to 10-kHz octave band noise at 108 dB … jena laser